Activation of the innate immune system is a key component in the development and progression of cardiovascular diseases. The focus of the experimental research conducted by the Schüchtermann-Klinik in close cooperation with the Max Planck Institute in Bad Nauheim is on identifying and characterising the factors and underlying mechanisms that determine the infiltration, activity and residence time of immune cells at the site of damage.

Local, intercellular interactions between the inflammatory cells and adjacent cell layers are also investigated, and the pathophysiological relevance of biological adaptation mechanisms is explored. Based on this, intervention strategieswill be derived and created to support endogenous cardiovascular healing processes.

The working group has many years of expertise in the use of cardiovascular disease models. In particular, flow cytometry, molecular biology, biochemistry, histology and cell culture methods are used for further investigation and interpretation.

You can also find out more about the working group’s activities on the pages of the MAX PLANCK INSTITUTE in BAD NAUHEIM.